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MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL (CRAC) INHIBITORS

机译:钙释放激活钙通道(CRAC)抑制剂的调节剂

摘要

Disclosed are novel calcium release-activated calcium (CRAC) channelinhibitors,methods for preparing them, pharmaceutical compositions containing them, andmethods oftreatment using them. The present disclosure also relates to methods fortreating non-small celllung cancer (NSCLC) with CRAC inhibitors, and to methods for identifyingtherapeutics fortreating and of diagnosing cancer.
机译:公开了新颖的钙释放激活钙(CRAC)通道抑制剂,制备它们的方法,包含它们的药物组合物和方法使用它们进行治疗。本公开还涉及用于治疗非小细胞CRAC抑制剂治疗肺癌(NSCLC)及其方法疗法治疗和诊断癌症。

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