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Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
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机译:用于系统递送生长停滞,脂质衍生的生物活性化合物的方法和系统
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摘要
A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
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