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DPP-IV inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating a diabetes or an obesity

机译:包含β-氨基的DPP-IV抑制剂,其制备方法和包含该抑制剂的药物组合物用于预防和治疗糖尿病或肥胖症

摘要

The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
机译:本发明提供了一种新型的含有β-氨基的杂环化合物,其制备方法以及包含该杂环化合物或其药学上可接受的盐作为活性成分的药物组合物。本发明的杂环化合物表现出优异的DPP-IV抑制活性和生物利用度,因此可用于预防或治疗与DPP-IV有关的疾病,例如糖尿病或肥胖症。

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