METHOD FOR ESTIMATING THE RISK OF HAVING OR DEVELOPING MULTIPLE SCLEROSIS USING SEQUENCE POLYMORPHISMS IN A SPECIFIC REGION OF CHROMOSOME X

摘要

The present invention provides methods for identifying human subjects with an increased risk of having or developing multiple sclerosis, as well as for estimating the prognosis for multiple sclerosis of an individual and for estimating a treatment response of an individual suffering or at risk of suffering from multiple sclerosis. In particular, this invention relates to the identification and characterization of polymorphisms positioned in or near human endogenous retroviruses on the human chromosome X, 3, 6, 16 and 19. The invention also discloses use of anti-viral compounds in the combat of multiple sclerosis.