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SPERM CELL SEPARATION METHODS AND COMPOSITIONS CONTAINING SPERM CELL TARGETING LIGANDS FOR USE THEREIN
SPERM CELL SEPARATION METHODS AND COMPOSITIONS CONTAINING SPERM CELL TARGETING LIGANDS FOR USE THEREIN
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机译:包含用于其中的精细胞靶向性配体的精细胞分离方法和成分
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摘要
The present invention provides sperm cell targeting ligands, including DNA-binding proteins, that bind target molecules on the surface of, accessible from the surface of, or inside mammalian sperm cells and methods for producing the sperm cell targeting ligands. The sperm cell targeting ligands are used to separate sperm cells based upon sperm cell qualities, such as whether the cells contain X chromosomes or Y chromosomes. The invention also provides methods of sperm cell purification using targeted radiofrequency absorption enhancers and transgenic animals with sex-skewed ejaculate.
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