首页> 外国专利> ORAL SUSPENSION OF DEXAMETHASONE ACETATE -TASTE MASKING COMPOSITION OF DEXAMETHASONE

ORAL SUSPENSION OF DEXAMETHASONE ACETATE -TASTE MASKING COMPOSITION OF DEXAMETHASONE

机译:醋酸地塞米松的口腔悬浮液-地塞米松的味觉成分

摘要

The present invention is a pharmaceutically acceptable composition in the form of suspension for the oral delivery of dexamethasone acetate in which the active ingredient is homogenously dispersed in a pharmaceutically acceptable aqueous carrier -vehicle. The present invention relates to a method for taste masking the bad taste of dexamethasone, provide a pharmaceutical composition comprising a specific ester of dexamethasone (dexamethasone acetate), in a therapeutically effective amount in a aqueous, compatible, stable media vehicle and a suspending agent The inventive formulation comprising dexamethasone acetate dispersed in an aqueous, compatible, between about 0.4 mg/ml to about 40 mg/ml, more preferably between 0.4 mg/ml to about 10mg/ml,more preferably 4 mg/ml. The aqueous vehicle may further consist of glycerin and propylene glycol. The inventive composition, comprises more than one pharmaceutical excipients.
机译:本发明是用于口服递送醋酸地塞米松的悬浮液形式的药学上可接受的组合物,其中活性成分均匀地分散在药学上可接受的水性载体-载体中。本发明涉及掩盖地塞米松不良味道的味道的方法,提供了一种药物组合物,该药物组合物包含治疗有效量的地塞米松特定酯(醋酸地塞米松乙酸酯)在水性,相容性,稳定的介质载体中和悬浮剂。本发明的制剂包含分散在约0.4mg / ml至约40mg / ml,更优选0.4mg / ml至约10mg / ml,更优选4mg / ml的相容水溶液中的乙酸地塞米松乙酸酯。水性载体可以进一步由甘油和丙二醇组成。本发明的组合物包含一种以上的药物赋形剂。

著录项

  • 公开/公告号WO2010119300A3

    专利类型

  • 公开/公告日2011-03-24

    原文格式PDF

  • 申请/专利权人 CASSO PHARMACEUTICALS LTD.;KASSOTAKIS ANGELOS;

    申请/专利号WO2010GR00018

  • 发明设计人 KASSOTAKIS ANGELOS;

    申请日2010-04-14

  • 分类号A61K9/10;A61K31/573;

  • 国家 WO

  • 入库时间 2022-08-21 18:00:42

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