METHODS FOR DIAGNOSING BENIGN VERSUS MALIGNANT THYROID LESIONS

摘要

The invention relates to methods for determining whether a thyroid nodule is malignant or benign. In particular, the present invention relates to a method for determining whether a thyroid nodule in a subject is benign or malignant said method comprising the steps of: providing a thyroid nodule sample previously collected from the said subject; and determining the level of expression of helicase-like transcription factor (HLTF) protein or a fragment thereof in a thyroid tissue sample from the subject, wherein said level of expression is indicative whether the nodule is benign or malignant.