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HUMAN CELL LINES SHOWING STABLE EXPRESSION OF CYTOCHROMES P450
HUMAN CELL LINES SHOWING STABLE EXPRESSION OF CYTOCHROMES P450
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机译:人细胞系显示细胞色素P450的稳定表达
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摘要
This invention relates to cell lines that obtained using cultured cell lines as a host and stably express a number of human cytochromes P450. The human liver-derived cultured cell lines of the present invention are useful in, for example, analyzing an enzyme participating in the metabolism of xenobiotics or endogenous substrates, because of their stable expression of human cytochromes P450 CYP1A1, 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1 and 3A4.
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