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ENZYME FRAGMENT COMPLEMENTATION ASSAYS FOR MONITORING THE ACTIVATION OF THE VOLTAGE-GATED POTASSIUM ION CHANNEL HERG
ENZYME FRAGMENT COMPLEMENTATION ASSAYS FOR MONITORING THE ACTIVATION OF THE VOLTAGE-GATED POTASSIUM ION CHANNEL HERG
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机译:用于监测电压门控钾离子通道HERG活化的酶片段互补测定
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摘要
The present invention provides methods and cell based assays for testing for the binding of a ligand to a human Ether-a-go-go-related (hERG) voltage-gated potassium ion channel protein in an enzyme complementation assay. The invention is of particular use in toxicological and drug screening, particularly for high throughput screening.
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