首页> 外国专利> FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING COMPRISING THE COMPOUND, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING AMINOMETHYL-AROMATIC RING USING THE AMINOMETHYLATING AGENT

FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING COMPRISING THE COMPOUND, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING AMINOMETHYL-AROMATIC RING USING THE AMINOMETHYLATING AGENT

机译:氟硼化合物,由该化合物组成的芳香环的氨基缩合剂,以及使用该胺化衍生物的具有氨基-芳香环的化合物的生产方法

摘要

A production method of a compound containing a primary, secondary, or tertiary aminomethyl aromatic ring of the present invention includes: using a fluoroboron compound or a dimer thereof, or solvates thereof, which are represented by a formula (I):        Ra(Rb)N-CH2-BF3M     (I)as an aminomethylating agent for an aromatic ring; and reacting the aminomethylating agent with an aromatic ring-containing compound, which can react with the aminomethylating agent, under the presence of a metal catalyst such as a palladium compound so as to perform the direct aminomethylation of the aromatic ring.
机译:本发明的包含伯,仲或叔氨基甲基芳族环的化合物的制备方法包括:使用氟硼化合物或其二聚体或其溶剂化物,其由式(I)表示:Ra(Rb)N-CH 2 -BF 3 M(I)作为芳香环的氨基甲基化剂;在金属催化剂如钯化合物的存在下,使氨基甲基化剂与可与氨基甲基化剂反应的含芳环化合物反应,以进行芳环的直接氨基甲基化。

著录项

  • 公开/公告号EP2039697A4

    专利类型

  • 公开/公告日2011-05-25

    原文格式PDF

  • 申请/专利权人 EISAI R&D MANAGEMENT CO. LTD.;

    申请/专利号EP20070790554

  • 发明设计人 TANAKA KEIGO;

    申请日2007-07-10

  • 分类号C07F5/02;C07B43/04;C07B43/06;C07B61;C07C209/08;C07C211/27;C07C231/12;C07C233/03;C07C269/06;C07C271/12;C07D209/48;C07D295/02;

  • 国家 EP

  • 入库时间 2022-08-21 17:58:06

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号