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SYSTEMIC IMMUNOSUPPRESSION IN THE TREATMENT OF AGE RELATED MACULAR DEGENERATION AND DIABETIC RETINOPATHY

机译:全身免疫抑制治疗年龄相关性黄斑变性和糖尿病性视网膜病变

摘要

The invention provides a pharmaceutical composition comprising at least one anti-CD25 antibody composition and/or rapamycin or derivatives thereof, in a pharmaceutically and physiologically acceptable carrier, for use in an amount effective for use as a medicament for inhibiting the progression of choroidal neovascularization (CNV) and/or for reducing the amount of anti-VEGF treatments needed by the patient associated with the treatment of age-related macular degeneration (AMD) in a patient undergoing anti-VEGF treatment, and/or as a medicament for use in inhibiting the progression of diabetic retinopathy (DR), and/or for reducing the amount of anti-VEGF treatments needed by the patient associated with the treatment of DR in an amount effective to reduce the amount of anti-VEGF treatments needed by the patient.
机译:本发明提供了药物组合物,其在药学上和生理学上可接受的载体中包含至少一种抗CD25抗体组合物和/或雷帕霉素或其衍生物,其用量有效地用作抑制脉络膜新血管形成进展的药物( CNV)和/或用于减少接受抗VEGF治疗的患者中与年龄相关性黄斑变性(AMD)的治疗有关的患者所需的抗VEGF治疗的量,和/或用作抑制性药物糖尿病视网膜病变(DR)的发展和/或用于减少与DR的治疗相关的患者所需的抗VEGF治疗的量,其有效量可减少患者所需的抗VEGF治疗的量。

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