METHOD FOR SCREENING OF QUORUM SENSING INHIBITORS

摘要

The present invention relates to a vector comprising an expression cassette for screening quorum sensing inhibitors, which comprises a gene encoding a transcriptional regulator that recognizes and binds to acyl homoserine lactone, a gene encoding an inhibitor of antibiotic-degrading enzyme that is operably linked to a promoter regulated by the transcriptional regulator, and a gene encoding an antibiotic-degrading enzyme that is inhibited by the inhibitor of antibiotic-degrading enzyme, a method for screening a quorum sensing inhibitor and a quorum sensing inhibitor screened by the method.