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METHOD TO IMPROVE THE IMMUNOGENICITY OF VACCINE ANTIGENS BY MODIFICATION OF CLEAVAGE SITES IN HIV-1 GP 120
METHOD TO IMPROVE THE IMMUNOGENICITY OF VACCINE ANTIGENS BY MODIFICATION OF CLEAVAGE SITES IN HIV-1 GP 120
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机译:通过修饰HIV-1 GP 120中裂解位点提高疫苗抗原免疫性的方法
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摘要
Disclosed are novel methods for altering the immunogenicity of vaccine antigens by mutation of cleavage sites recognized by proteases involved in antigen presentation and processing. Also disclosed are therapeutic compositions, vaccines and methods for treating or preventing HIV and other viral diseases.
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