首页> 外国专利> METHOD FOR THE ELUTION OF 18F FLUORIDE TRAPPED ON AN ANION-EXCHANGE PHASE IN A FORM SUITABLE FOR EFFICIENT RADIOLABELING WITHOUT ANY EVAPORATION STEP

METHOD FOR THE ELUTION OF 18F FLUORIDE TRAPPED ON AN ANION-EXCHANGE PHASE IN A FORM SUITABLE FOR EFFICIENT RADIOLABELING WITHOUT ANY EVAPORATION STEP

机译:无需任何蒸发步骤即可将18F氟化物截留在阴离子交换相上的方法,该形式适用于有效的放射标记

摘要

The present invention relates to a method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step, characterised in that the eluting solution is a low water content, preferably 3% water, organic solution containing at least: - a first compound (A) which is a tertiary alcohol-function bearing molecule, - a second compound (B) which is a phase transfer agent suitable for radiolabeling and which is necessary to the anion exchange process.
机译:本发明涉及从水溶液中提取,浓缩和/或重新配制[18 F]氟化物而无需任何蒸发步骤的方法,其特征在于洗脱溶液是低水含量,优选<3%水,含有至少:-第一化合物(A),其为具有叔醇功能的分子,-第二化合物(B),其是适合于放射性标记并且是阴离子交换过程所必需的相转移剂。

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