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METHODS AND COMPOSITIONS RELATED TO PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS CROSS-REFERENCE TO RELATED APPLICATIONS

机译:与具有C末端元素的肽和蛋白质相关的方法和组成相关申请的交叉引用

摘要

Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
机译:公开了可用于将分子靶向和内在感兴趣细胞中以及可被感兴趣组织的分子穿透的组合物和方法。所述组合物和方法基于被细胞选择性地内在化,穿透组织或两者的肽序列。所公开的内化作用和组织渗透可用于将治疗剂和可检测剂递送至目的细胞和组织。

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