Identification of netrin-1 receptor unc5c gene mutation in solid cancers

摘要

The present invention relates to the identification of the UNC5C A628K, P57T, R603C, Q630C, A841Y or A628E variant implicated in solid cancer. A method is provided for the detection of these variants as shown in SEQ ID No 1 or 5 in solid cancers and to a screening test for predisposition to solid cancers, such as colorectal cancers.