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METHOD FOR STAGING MYOCARDIAL INFARCTION AND FOR MONITORING EFFICACY OF INTERVENTION

机译:减轻心肌梗塞和监测干预效果的方法

摘要

The present invention relates to a method for the stage of myocardial infarction in a subject showing a ST segment elevated myocardial infarction (STEMI). Moreover, the present invention relates to a method for identifying a subject being susceptible to cardiac intervention, wherein the subject suffers from a ST segment elevated myocardial infarction (STEMI). The methods of the present invention are based on the determination of soluble fms-like tyrosine kinase-1 (sFLT-1), heart fatty acid binding protein (H-FABP) and a cardiac troponin or a variant thereof in a sample of said subject, and comparing the amounts of sFLT-1, H-FABP, and the cardiac troponin to at least one reference amount. Also comprised by the present invention are kits or devices to carry out the methods of the present invention.
机译:本发明涉及一种在显示ST段升高的心肌梗塞(STEMI)的受试者中进行心肌梗塞的阶段的方法。此外,本发明涉及用于识别易受心脏干预的受试者的方法,其中所述受试者患有ST段升高的心肌梗塞(STEMI)。本发明的方法基于对所述受试者的样品中的可溶性fms样酪氨酸激酶-1(sFLT-1),心脏脂肪酸结合蛋白(H-FABP)和心肌肌钙蛋白或其变体的测定。 ,并将sFLT-1,H-FABP和心肌肌钙蛋白的量与至少一个参考量进行比较。本发明还包括进行本发明方法的试剂盒或装置。

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