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NEURO-PROTECTIVE EFFECTS OF ADELOSTEMMA GRACILLIMUM AND ITS ISOLATED COMPOUNDS

机译：骨肉瘤及其分离化合物的神经保护作用

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摘要

Isolated compounds from adelostemma gracillimum refined fractions and compositions containing the compounds are provided by the present invention. Adelostemma gracillimum refined fractions and the extraction process thereof are also provided by the present invention. The uses of the compounds and the adelostemma gracillimum refined fractions for inhibiting the activities of NMDA receptor or amyloid-beta peptide, for improving memory, and for treating neurodegenerative diseases, neuropathological conditions or epilepsy are further provided by the present invention.

机译：由本发明提供了从细叶鸢尾精制级分中分离的化合物和包含该化合物的组合物。本发明还提供了拟南芥精制馏分及其提取方法。本发明进一步提供了化合物和禾本科细提香的精制级分在抑制NMDA受体或淀粉样β肽的活性，改善记忆力以及治疗神经退行性疾病，神经病理学状况或癫痫中的用途。

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公开/公告号WO2011114220A1

专利类型
公开/公告日2011-09-22

原文格式PDF
申请/专利权人 BIOTECHNOLOGY RESEARCH CORPORATION LIMITED;IP NANCY YUK-YU;IP FANNY CHUI-FUN;GUO SHENGJUN;
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申请/专利号WO2011IB00567
发明设计人 IP NANCY YUK-YU;IP FANNY CHUI-FUN;GUO SHENGJUN;
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申请日2011-03-18
分类号A61K31/085;A61K31/357;A61K31/065;A61K31/343;A61K31/56;A61K31/22;A61K31/215;A61K36/27;C07C43/243;C07D319/20;C07C31/20;C07D307/78;C07C69/738;C07C69/003;C07J1;A61P25;A61P25/28;A61P25/08;
国家 WO
入库时间 2022-08-21 17:55:39

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