FUNCTIONALLY INTACT FIBRINOGEN REMAINING STABLE DURING STORAGE

摘要

Method for the production of a fibrinogen solution from an aqueous solution that contains functionally intact fibrinogen and is contaminated with profibrin and/or fibrin monomers and/or fibrin monomer complexes and/or fibrin split products, characterized in that the contaminations are precipitated using a non-denaturing precipitating agent at a temperature ranging from 4° to +4° and calcium ion activity not exceeding that of a 1,000 M CaCl2 solution and are separated from the solution by means of filtering or centrifugation process.