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Immobilized probes and methods of detecting conformationally altered prion proteins
Immobilized probes and methods of detecting conformationally altered prion proteins
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机译:固定探针和检测构象改变的pr病毒蛋白的方法
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摘要
The present invention provides methods of making immobilized probes that are specific for prion proteins, methods of using such probes to bind, detect, and remove prion proteins from samples, and kits for practicing the invention. The invention discloses immobilized probes that are locked into a particular, pre-determined configuration and that retain their activity and specificity even when exposed to conditions that would typically alter their activity and specificity.
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