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METHOD FOR DETERMINING THE RESISTANCE STATUS OF FUNGI AND YEASTS, IN PARTICULAR OF ASPERGILLUS FUMIGATUS
METHOD FOR DETERMINING THE RESISTANCE STATUS OF FUNGI AND YEASTS, IN PARTICULAR OF ASPERGILLUS FUMIGATUS
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机译:测定曲霉菌和真菌的抵抗力状态的方法
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摘要
The invention relates to a method for determining the resistance status of fungi and yeasts in a body sample of a patient suspected of having an invasive infection, comprising the steps of isolating DNA from a body sample of the patient, identifying mutations in a gene of the fungus or yeast, and correlating the resistance status of the fungus or yeast to the mutations found, wherein the body sample is blood or a blood derivative or a sample of an organ, and is in particular serum. Suitably, the method is performed in closed-tube format. The method of the invention is particularly suitable when the fungus of which the resistance status is to be determined is Aspergillus fumigatus.
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