UGT1A6 GENE SNP MARKERS ASSOCIATED WITH SERUM BILIRUBIN CONCENTRATION AND USES THEREOF

摘要

PURPOSE: A kit for predicting blood bilirubin concentration of a test sample and a method for detecting a bilirubin marker are provided to easily diagnose hyperbilirubinemia. CONSTITUTION: A kit for predicting blood bilirubin concentration of a test sample contains: 8-100 sequential nucleotide sequences having single nucleotide polymorphism(SNP) positioned at 301th nucleotide of sequence number 1-4, 8-11 and 13, 314th nucleotide of sequence number 5, 201th nucleotide of sequence number 6, 234th nucleotide of sequence number 7, 308th nucleotide of sequence number 12, 307th nucleotide of sequence number 14, and 136th nucleotide of sequence number 15; and a complementary nucleotide thereof. The prediction of bilirubin concentration is used for diagnosing hyperbilirubinemia, jaundice, Gilbert syndrome, Dubin-Johnson syndrome, Rotor syndrome, or Crigler-najjar syndrome.