MONOCLONAL ANTIBODY FOR IDENTIFYING AND DETECTING ABNORMAL PRION OF SPONGIFORM ENCEPHALOPATHY AND A FUSION CELL LINE PRODUCING THE SAME

摘要

PURPOSE: A monoclonal antibody for specifically detecting abnormal prion of spongiform encephalopathy is provided.;CONSTITUTION: A fusion cell line of deposit number KCLRF-BP-00213 produces monoclonal antibody for detecting abnormal prion of spongiform encephalopathy. A method for preparing fusion cell line comprises: a step of inoculating a peptide of sequence number 1 to a knock-out mouse; a step of isolating B cells from the mouse; and a step of fusing the B cells and mouse myeloma-derived cells. The abnormal prion of spongiform encephalopathy is detected by western blotting using the monoclonal antibody.;COPYRIGHT KIPO 2011