TWO PHOTON FLUORESCENT PROBE WITH SELECTIVITY OF CALCIUM ION AND A METHOD FOR IMAGING CLACIUM ION USING THE SAME

摘要

PURPOSE: A two photon fluorescent probe with selectivity of calcium ion in a cell and tissue is provided to effectively make an image of calcium ions near cells and tissues.;CONSTITUTION: A two photon fluorescent probe of chemical formula 1 has selectivity of calcium ion in a cells and tissue. The probe of chemical formula having calcium ion selectivity 1 is prepared by reacting a compound of chemical formula 3 and a compound of chemical formula 4. An image of intracellular calcium ion is made by two-photon excited fluorescence(TPEF) using the probe at 360-620 nm of wave length.;COPYRIGHT KIPO 2011