NEUROPROTECTIVE CONSTITUENTS OF ERAGROSTIS FERRUGINEA AGAINST AINDUCED TOXICITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

摘要

The present invention is an extract that has the activity of inhibiting brain cell damage by beta amyloid and the active ingredient tricin (tricin, compound 2), ageconyflavone (ageconyflavone A, compound 3), nectandrin B (nectandrin B) isolated from the extract , Compound 5) and 4-ketopinolesinol (4-ketopinoresinol, Compound 6) and a pharmaceutical composition for preventing or treating amyloid-related diseases containing the same. Heyeong extract and its active ingredient according to the present invention is a natural product extract relatively low side effects and toxic expression rate, bio-friendly and useful for the prevention or treatment of amyloid-related diseases such as Alzheimer's disease, Down syndrome, cognitive impairment, memory loss and amyloidosis Can be used.