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A COMPOSITION FOR TREATING DISEASE CAUSED BY NEURONAL INSULT COMPRISING SCHWANN CELL-LIKE CELLS THAT SECRETING HIGH AMOUNT OF GROWTH FACTORS AS ACTIVE INGREDIENTS
A COMPOSITION FOR TREATING DISEASE CAUSED BY NEURONAL INSULT COMPRISING SCHWANN CELL-LIKE CELLS THAT SECRETING HIGH AMOUNT OF GROWTH FACTORS AS ACTIVE INGREDIENTS
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机译:一种用于治疗神经疾病的组合物,该组合物包括分泌大量生长因子作为活性成分的施万氏细胞样细胞
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摘要
The present invention relates to a therapeutic agent for nerve injury cells containing Schwann cells as an active ingredient. Specifically, Schwann cells differentiated from human mesenchymal stem cells of the present invention are hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF). Overexpressing HGF and VEGF through the secretion of nerve cells and spinal cord tissue sections of the damaged spinal cord of the nerve fibers and cells to increase the growth and suppression of cell death to act directly as a growth factor As confirmed, the differentiated Schwann cells of the present invention are a composition for delivery of HGF or VEGF in a subject for treatment or improvement of a subject having a neurological disorder and a cell therapeutic agent derived from autologous tissue without genetic manipulation for treating a nervous system injury. It can be used easily.
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