Production method of de-differentiation starch Mars stem cells using the herpes simplex virus amplicon that includes the de-differentiation inducer

摘要

The present invention (a) de-differentiation inducing factor coding for genes containing the herpes simplex amplicon virus (Herpes simplex amplicon viruses) exist under the man on the derived somatic cells or immortalized with (immortalized) cell line culture that stage; And (b) an embryonic stem cell from a culture obtained from (a) - similar to colonies comprising the step of separating (embryonic stem cell-like colonies), provides a method for producing de-differentiation pluripotent stem cells (iPS cells) . ; Herpes simplex virus amplicon, de-differentiation pluripotent stem cells