Human CIB protein and CIB gene thereof preventing stress-induced cell death

摘要

The present invention relates to a Calcium and integrin binding protein 1 (CIB1) protein that inhibits apoptosis, a CIB1 gene encoding the protein, and a use thereof, and specifically, to yeast 2-hybrid screening. It relates to the CIB1 protein, the CIB1 gene, and its use in combination with the apoptosis signal-regulating kinase ASK1 (apoptosis signal-regulating kinase 1), which inhibit cell death. The human CIB1 protein or CIB1 gene of the present invention may be used as a selective inhibitor of ASK1-mediated cell death or may be useful for the treatment, prevention, diagnosis or research process of degenerative neurological diseases such as Parkinson's disease and immune system diseases. .;CIB1, ASK1, Calcium, Apoptosis