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Amine derivatives of monascus pigment inhibiting differentiation of preadipocyte 3T3-L1 cells

机译:红曲霉色素的胺衍生物抑制前脂肪细胞3T3-L1细胞的分化

摘要

The present invention relates to a composition for preventing or treating obesity, comprising an amine derivative compound of a Monascus pigment that inhibits the differentiation of adipose progenitor cells, and a pharmaceutically acceptable carrier, wherein the fungus bacterium Monascus sp. The amine derivative compound synthesized by liquid culture of J101 (KCCM 10093) to produce a Monascus orange pigment and reacted with an amine compound inhibits the differentiation process of 3T3-L1, which is a progenitor cell, resulting in obesity. It is useful for preventing or treating obesity by inhibiting accumulation.;Monascus, Progenitor Cell, Differentiation
机译:本发明涉及用于预防或治疗肥胖症的组合物,其包含抑制脂肪祖细胞分化的红曲霉色素的胺衍生物化合物和药学上可接受的载体,其中真菌细菌红曲霉 sp 。通过J101(KCCM 10093)的液体培养合成的红曲胺生成红曲橙颜料,并与胺化合物反应会抑制作为祖细胞的3T3-L1的分化过程,从而导致肥胖。可通过抑制积累来预防或治疗肥胖。红曲霉,祖细胞,分化

著录项

  • 公开/公告号KR101079800B1

    专利类型

  • 公开/公告日2011-11-04

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20090033187

  • 发明设计人 신철수;우수현;

    申请日2009-04-16

  • 分类号A61K31/4741;A61P3/04;A23L1/30;

  • 国家 KR

  • 入库时间 2022-08-21 17:49:30

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