PREDICTION METHOD OF EFFICIENCY immunotherapy based on evaluation of the expression level of cytokine mRNA in a tissue KIDNEY CANCER

摘要

FIELD: medicine.;SUBSTANCE: invention relates to the field of medicine. Claimed is a method of determining sensitivity of kidney cancer to immunotherapy after performing nephrectomy, including diagnosis verification, performing nephrectomy of kidney cancer, sampling of tumour and normal kidney tissue to determine a level of expression of cytokines IL-4, IL-6, IL-10, TGFβ and calculation of ratio of level of cytokine expression in tumour and normal kidney tissue. If the level of cytokine expression in tumour tissue of kidney is higher than normal, therapy is considered to be indicated.;EFFECT: invention makes it possible to determine sensitivity of kidney cancer to immunotherapy on the basis of the data of cytokine expression in tumour tissue.;2 tbl, 1 ex