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Pharmaceutical compositions for topical antibacterial, anti-inflammatory and immunomodulatory effects, AND ITS APPLICATIONS

机译:具有局部抗菌,消炎和免疫调节作用的药物组合物及其应用

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: disclosed is use of a combination containing a therapeutically effective amount of a pharmaceutically acceptable zinc compound, ascorbic acid or a pharmaceutically acceptable salt thereof and succinic acid or a pharmaceutically acceptable salt thereof for improving effectiveness of antibacterial drug chlorhexidine or chlorhexidine bigluconate, including a pharmaceutical composition for local application or pharmaceutical preparation for local application, wherein said pharmaceutical composition or pharmaceutical preparation contains pharmaceutically acceptable additives.;EFFECT: invention enables to use antibacterial agents in considerably reduced concentrations in pharmaceutical preparations or use said pharmaceutical preparations in smaller doses; also, for chlorhexidine combination with zinc oxide, ascorbic and succinic acids provided immunomodulatory and anti-exudative action of pharmaceutical composition.;1 cl, 7 tbl, 6 ex
机译:领域:医学;物质:公开了包含治疗有效量的药学上可接受的锌化合物,抗坏血酸或其药学上可接受的盐和琥珀酸或其药学上可接受的盐的组合在提高抗菌药物洗必太或洗必太双葡萄糖酸酯的有效性中的用途。 ,包括用于局部应用的药物组合物或用于局部应用的药物制剂,其中所述药物组合物或药物制剂包含药学上可接受的添加剂。效果:本发明使得能够在药物制剂中使用浓度大大降低的抗菌剂或以较小的剂量使用所述药物制剂。剂量同样,对于氯己定与氧化锌的组合,抗坏血酸和琥珀酸可提供药物组合物的免疫调节和抗渗出作用。; 1 cl,7 tbl,6 ex

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