首页> 外国专利> APPLICATION OF BETA-MELANOTROPINE AS A THERAPEUTIC, FOR EXAMPLE, FOR THE TREATMENT OF AIDS OR ALZHEIMER'S DISEASE

APPLICATION OF BETA-MELANOTROPINE AS A THERAPEUTIC, FOR EXAMPLE, FOR THE TREATMENT OF AIDS OR ALZHEIMER'S DISEASE

机译:β-美拉诺汀作为治疗药物的应用,例如,用于治疗艾滋病或阿兹海默氏病

摘要

1. The use of the peptide Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp-OH for obtaining a pharmaceutical composition for the treatment and / or prevention of a malignant tumor, autoimmune diseases, fibrosis, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and blood vessel diseases and metabolic diseases. ! 2. The use of the peptide according to claim 1, where the malignant tumor, autoimmune disease, fibrosis, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and blood vessel disease or metabolic disease are selected from amyotrophic lateral sclerosis, ischemic damage to the kidney, retinitis pigmentosa , epilepsy, aplastic anemia, myelodysplastic syndrome, CD4 + T-cell lymphocytopenia, G6PDH deficiency, polycystic kidney, acute liver failure, acute tubule necrosis induced by Streptococcus pneumoniae and epithelial cell death. ! 3. The use of the peptide according to claim 1 or 2 to obtain a composition for oral administration to newborns, toddlers and / or preschool children. ! 4. The use of the peptide according to claim 1 or 2 to obtain a lyophilized composition or a buffer liquid composition. ! 5. A pharmaceutical composition comprising the peptide Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp -OH, at least in conjunction with one pharmaceutically acceptable carrier, cryoprotectant, lyoprotector, excipient and / or diluent. ! 6. The pharmaceutical composition according to claim 5 in the form of a lyophilisate or a liquid buffer solution. ! 7. The pharmaceutical composition according to claim 5 or
机译:1.肽Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp的用途-OH,用于获得用于治疗和/或预防恶性肿瘤,自身免疫性疾病,纤维化,炎性疾病,神经退行性疾病,感染性疾病,肺部疾病,心脏和血管疾病以及代谢性疾病的药物组合物。 ! 2.根据权利要求1的肽的用途,其中所述恶性肿瘤,自身免疫疾病,纤维化,炎性疾病,神经退行性疾病,感染性疾病,肺部疾病,心脏和血管疾病或代谢性疾病选自肌萎缩性侧索硬化,缺血肾脏损害,色素性视网膜炎,癫痫,再生障碍性贫血,骨髓增生异常综合症,CD4 + T细胞淋巴细胞减少,G6PDH缺乏,多囊肾,急性肝衰竭,肺炎链球菌引起的急性肾小管坏死和上皮细胞死亡。 ! 3.根据权利要求1或2所述的肽在获得用于新生儿,学步儿童和/或学龄前儿童的口服给药的组合物中的用途。 ! 4.根据权利要求1或2的肽在获得冻干组合物或缓冲液组合物中的用途。 ! 5.药物组合物,其包含肽Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys- Asp-OH,至少与一种药学上可接受的载体,冷冻保护剂,冻干保护剂,赋形剂和/或稀释剂结合。 ! 6.根据权利要求5的药物组合物,其为冻干物或液体缓冲溶液的形式。 ! 7.根据权利要求5或6的药物组合物,

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