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The combination of splenopentin and thymopentin and their use in the drug

机译:脾脏开放素和胸腺五肽的组合及其在药物中的用途

摘要

1. The combination of the peptides Arg-Lys-Glu-Val-Tyr-OH and Arg-Lys-Asp-Val-Tyr-OH or their salts or hydrates. ! 2. The combination according to claim 1, where the peptides are contained in combination in an amount of from 30 wt.% To 70 wt.% To 70 wt.% To 30 wt.%. ! 3. The combination according to claim 1 for use in a medicinal product. ! 4. The use of the combination according to claims 1, 2 or 3 to obtain a pharmaceutical composition for the treatment and / or prevention of a malignant tumor, autoimmune diseases, fibrosis, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and blood vessels diseases and metabolic diseases . ! 5. The use of the combination according to claim 4, where the malignant tumor, autoimmune disease, fibrosis, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and vascular disease or metabolic disease are selected from vasculitis and excessive angiogenesis in autoimmune diseases, systemic sclerosis , multiple sclerosis, Sjogren's syndrome, vascular deformities in the networks of blood and lymph vessels, DiGeorge syndrome, congenital hemorrhagic telangiectasia, cavernous g mangiomas, cutaneous hemangiomas, lymphatic vessel deformities, graft arteriopathy, atherosclerosis, vascular anastomoses, adipose tissue in case of obesity, chronic allograft rejection, skin diseases, psoriasis, papillomas, allergic dermatitis, keloid scar, pyogenic granuloma, anorexa ulcer, AIDS, systemic sclerosis, eye diseases, persistent vitreous hyperplastic syndrome, diabetic retinopathy, premature retinopathy
机译:1.肽Arg-Lys-Glu-Val-Tyr-OH和Arg-Lys-Asp-Val-Tyr-OH或其盐或水合物的组合。 ! 2.根据权利要求1的组合,其中所述肽的组合含量为30重量%至70重量%至70重量%至30重量%。 ! 3.根据权利要求1的组合,用于药物。 ! 4.根据权利要求1、2或3的组合的用途,用于获得用于治疗和/或预防恶性肿瘤,自身免疫性疾病,纤维化,炎性疾病,神经退行性疾病,传染病,肺病,心脏的药物组合物以及血管疾病和代谢疾病。 ! 5.根据权利要求4的组合的用途,其中所述恶性肿瘤,自身免疫性疾病,纤维化,炎性疾病,神经退行性疾病,感染性疾病,肺部疾病,心脏和血管疾病或代谢性疾病选自自身免疫中的血管炎和过度血管生成疾病,全身性硬化症,多发性硬化症,干燥综合征,血管和淋巴血管网络中的血管畸形,DiGeorge综合征,先天性出血性毛细血管扩张症,海绵状血管瘤,皮肤血管瘤,淋巴管畸形,移植动脉病,动脉粥样硬化,血管吻合,脂肪如果患有肥胖症,慢性同种异体移植排斥反应,皮肤疾病,牛皮癣,乳头状瘤,过敏性皮炎,瘢痕loid,化脓性肉芽肿,厌食性溃疡,艾滋病,全身性硬化症,眼病,持续性玻璃体增生综合症,糖尿病性视网膜病,过早视网膜病

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