METHOD OF DIFFERENTIAL DIAGNOSTICS OF HEPATIC FIBROSIS IN CASE OF CHRONIC VIRAL HEPATITIS C

摘要

FIELD: medicine.;SUBSTANCE: invention relates to field of medicine, namely to infectious diseases and hepatology. In order to carry out differential diagnostics of hepatic fibrosis in case of chronic viral hepatitic C patient's venous blood is analysed. Concentration of transforming growth factor -1β (TGF-1β) in blood serum is determined by method of solid-phase ELISA. If value of TGF-1β concentration is higher than 400 pg/ml, mild or moderate hepatic fibrosis is diagnosed. If TGF-1β value is lower than 400 pg/ml, severe fibrosis or hepatocirrhosis is diagnosed.;EFFECT: method is non-invasive, is characterised by high accuracy of differential diagnostics of hepatic fibrosis in case of chronic viral hepatitis C.;2 dwg, 6 ex, 3 tbl