VIRUS-LIKE PARTICLES INCLUDING HYBRID PROTEIN OF AP205 BACTERIOPHAGE COAT PROTEIN AND ANTIGEN POLYPEPTIDE

摘要

FIELD: medicine.;SUBSTANCE: modified virus-like particle (VLP) includes hybrid protein which consists of AP205 bacteriophage protein and any antigen. Also, a composition including VLP, being a derivative of RNA-containing AP205 bacteriophage is described. Besides, the invention describes a method for producing said VLP. Modified VLP of the present invention is applicable for producing compositions for inducing immune response for prevention or treatment of diseases, disorders, including infectious diseases, allergies, cancer and drug addiction.;EFFECT: offered group of inventions can be used in medicine, immunology, virology and molecular biology.;35 cl, 3 dwg, 1 tbl, 26 ex