METHOD FOR PREDICTION OF ATYPICAL ANTIPSYCHOTIC DRUG TREATMENT RATES IN SHIZOPHRENICS

摘要

FIELD: medicine.;SUBSTANCE: clinical investigation is supplemented with simultaneously testing monoamine oxidase (MAO) activity in thrombocytes in nmole of benzaldehyde per 1 mg of protein an hour and semicarbazide-dependent amine oxidase (CAO) activity in blood serum in nmole of benzaldehyde per one ml of blood serum an hour. The blood serum CAO to thrombocyte MAO activity relation is calculated. If the value exceeds 0.6, a positive result of atypical antipsychotic drug treatment in schizophrenia is predicted.;EFFECT: more precise and objective prediction, reduced length of treatment in schizophrenics.;2 ex