METHOD OF DIFFERENTIAL DIAGNOSTICS OF PRIMARY OPEN-ANGLE GLAUCOMA IN PATIENTS WITH PROGRESSING MYOPIA

摘要

FIELD: medicine.;SUBSTANCE: invention relates to field of medicine, in particular to ophthalmology, and can be used for diagnostics of clinical version of primary open-angle glaucoma (POAG) in patients with progressing myopia. In patients with progressing myopia by method of transcranial duplex scanning initial value of maximal systolic rate of blood flow (V_{max 0}) in medial cerebral artery (MCA) is determined. After that hypercapnia test is performed and value of maximal systolic rate of blood flow in MCA is determined after hypercapnia test (Vmaxi).15-20 minutes later hypercapnic test is performed and value of maximal systolic rate of blood flow in MCA is determined after hypercapnia test (V_{max 2}). After carrying out tests by formulas calculated are increase of V_max1 and reduction of V_max2, % ;where δ V_max1 is increase of V_max1 in MCA, %, δ V_max2 is reduction of V_max2 in MCA, %. After that day monitoring of arterial pressure is performed and determined are values of average day systolic (SAP_aver) and diastolic (DAP _aver) pressure, variability of systolic arterial pressure during day (VSAP_d) and night (VSAP_n), variability of diastolic arterial pressure during day (VDAP_d) and night (VDAP_n). If value of δ ,V_max130%, SAP_aver≤ 105.0 mm Hg, DAP_aver ≤ 70.0 mm Hg, VSAP_d ≥ 10.0 mm Hg VDAP_n ≥ 9.0 mm Hg, discircular version of POAG is diagnosed; if value of δ V_max230%, SAP_aver≥ 115.0 mm Hg, DAP _aver ≥ 75.0 mm Hg, VSAP_d≤ 10.0 mm Hg, VDAP_n ≤ 9.0 mm Hg, ischemic version of POAG is diagnosed.;EFFECT: method makes it possible to perform differential diagnostics of clinic versions of POAG in patients with progressing myopia at early stages of disease with high degree of accuracy.;2 ex