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Method and device for the elevation of measurement signals of vital tissue

机译:提升重要组织的测量信号的方法和装置

摘要

The invention is directed to a method and a measurement device for recording spectrometric measurement signals from vital tissue. The object of the invention is to provide solutions by which, in the course of a spectrometric measurement, it is possible to generate measurement values which, compared to aforementioned previous recording methods, provide more comprehensive information. According to the invention, this object is achieved by a method which generates spectrometric measurement signals and in which light is coupled into an area of vital tissue to be examined, reflected light issuing as such from the tissue area to be examined is fed to a spectrometry device, and the spectrometry device generates measurement signals which as such represent the intensity of the reflected light with respect to the wavelength, wherein the measurement proceeds in such a way that it extends over a period of time, and within this period of time the presence of haemoglobin in the examined tissue section is actively changed by changing the tissue pressure, wherein the spectra determined in succession for different tissue pressures are used in order to determine changes in the spectra induced by the haemoglobin concentration, and, from these different spectra, the concentrations of selected substances in the tissue section are calculated. In this way, it is advantageously possible to generate, in relatively quick succession, several spectra relating to the tissue section under examination, wherein these spectra have differences ("distortions") caused by actively induced changes of the tissue pressure, and said differences as such are sufficient for determining the concentration of substances to be detected within the vascularizing areas of the tissue system.
机译:本发明涉及一种用于记录来自重要组织的光谱测量信号的方法和测量设备。发明内容本发明的目的是提供一种解决方案,通过该解决方案在光谱测量过程中可以产生测量值,与前述的先前的记录方法相比,该测量值可以提供更全面的信息。根据本发明,该目的通过一种方法来实现,该方法产生光谱测量信号,并且其中将光耦合到要检查的重要组织区域中,将这样从要检查的组织区域发出的反射光馈送到光谱仪中。装置和光谱仪产生测量信号,这些信号代表反射光相对于波长的强度,其中测量以这样一种方式进行,即它会在一段时间内延伸,并且在此期间内通过改变组织压力积极地改变被检查组织部分中血红蛋白的含量,其中使用针对不同组织压力连续确定的光谱以确定由血红蛋白浓度引起的光谱变化,并从这些不同光谱中确定计算组织部分中所选物质的浓度。以这种方式,有利地可以相对快速地连续地产生与被检查的组织切片有关的几个光谱,其中这些光谱具有由主动引起的组织压力变化引起的差异(“畸变”),并且所述差异为这足以确定组织系统的血管化区域内要检测的物质的浓度。

著录项

  • 公开/公告号DE112009000264A5

    专利类型

  • 公开/公告日2011-03-03

    原文格式PDF

  • 申请/专利权人

    申请/专利号DE20091100264T

  • 发明设计人

    申请日2009-02-25

  • 分类号A61B5/00;

  • 国家 DE

  • 入库时间 2022-08-21 17:47:30

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