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Encochleated antifungal compounds for central nervous system delivery and treatment of Cryptococcus infections

机译：用于中枢神经系统递送和治疗隐球菌感染的包被的抗真菌化合物

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摘要

The present application is directed to a cochleate composition including one or more cochleates and at least two antifungal compounds selected from amphotericin B, 5 -flucytosine, fluconazole, ketoconazole, ravuconazole, albaconazole, itraconazole, posaconazole, isavuconazole and/or voriconazole. Methods of using the antifungal cochleate formulations are also disclosed.

机译：本申请涉及一种耳蜗组合物，其包含一种或多种耳蜗和至少两种选自两性霉素B，5-氟胞嘧啶，氟康唑，酮康唑，拉伏康唑，阿尔巴康唑，伊曲康唑，泊沙康唑，异氟康唑和/或伏立康唑的抗真菌化合物。还公开了使用抗真菌的耳蜗制剂的方法。

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公开/公告号AU2017297402A1

专利类型
公开/公告日2019-01-03

原文格式PDF
申请/专利权人 MATINAS BIOPHARMA NANOTECHNOLOGIES INC.;
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申请/专利号AU20170297402
发明设计人 MANNINO RAPHAEL J.;LU RUYING;KLING DOUG F.;
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申请日2017-07-12
分类号A61K9/127;A61K31;A61K31/7048;
国家 AU
入库时间 2022-08-21 17:46:07

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