CONTROLLED RELEASE PHARMACEUTICAL FORMULATION, UNIT DOSE FORM, DRY GRANULE, MULTIPARTICULATE, PREPARATION METHOD, USE OF COPOLYMER, AND METHOD FOR IMPARTING TAMPER RESISTANCE TO PHARMACEUTICAL FORMULATION

摘要

PROBLEM TO BE SOLVED: To provide a neutral poly (ethyl acrylate, methyl methacrylate) copolymer employed as a carrier in the manufacture of pharmaceutical formulations containing an active ingredient.SOLUTION: In the manufacturing of pharmaceutical formulations containing an active ingredient, the neutral poly (ethyl acrylate, methyl methacrylate) copolymer is employed as a carrier, and the formulations are preferably made by melt extrusion, and can have rubbery characteristics and can exhibit tamper resistance.