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SPECTRUM EXTRACTION METHOD FOR BIOLOGICAL SAMPLE, AND SPECTRAL IMAGE GENERATION METHOD

机译:生物样品的光谱提取方法及光谱图像生成方法

摘要

PROBLEM TO BE SOLVED: To improve diagnostic precision of pathology diagnosis by acquiring a dyeing image and a spectral imaging image using the same sample without changing a conventional dyeing-premised pathology diagnostic process.;SOLUTION: There is provided a spectrum extraction method including: steps S22, S23 of acquiring a first spectral data set having a spectroscopy spectrum defining a dyeing pigment structure present in a dyed biological sample and a second spectral data set having a spectroscopy spectrum containing a biological sample, a dyeing pigment, and other contents; a step S24 of selecting a dyeing condition having a spectroscopy spectrum approximating the first spectroscopy spectrum data set most from a database; a step S25 of selecting a spectroscopy spectrum of a dyeing pigment corresponding to the selected dyeing condition from a spectroscopy database; a step S26 of generating a spectroscopy reference; and a step S27 of removing spectroscopy spectra of the dyeing pigment and contents from the second spectral data set through mathematical processing using the spectroscopy reference.;COPYRIGHT: (C)2013,JPO&INPIT
机译:解决的问题:通过使用相同的样本获取染色图像和光谱成像图像,而无需改变传统的染色病理诊断过程,从而提高病理诊断的诊断精度。解决方案:提供了一种光谱提取方法,包括:步骤S22,S23,获取具有光谱光谱的第一光谱数据集,该光谱光谱定义了存在于染色生物样品中的染料色素结构,以及具有光谱光谱的第二光谱数据集,该光谱光谱包含生物样品,染料色素和其他成分。步骤S24,从数据库中选择具有最接近于第一光谱光谱数据集的光谱光谱的染色条件;步骤S25,从光谱数据库中选择与选择的染色条件相对应的染色颜料的光谱。步骤S26,生成光谱参考。步骤S27,通过使用光谱学参考文献进行数学处理,从第二光谱数据集中去除染色颜料的光谱和内容物。COPYRIGHT:(C)2013,JPO&INPIT

著录项

  • 公开/公告号JP2012202717A

    专利类型

  • 公开/公告日2012-10-22

    原文格式PDF

  • 申请/专利权人 OLYMPUS CORP;

    申请/专利号JP20110064996

  • 申请日2011-03-23

  • 分类号G01N21/65;G01N21/64;

  • 国家 JP

  • 入库时间 2022-08-21 17:44:46

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