COMPOSITION HAVING ANTICANCER ACTIVITY, CONTAINING INGREDIENT EXTRACTED FROM CORDYCEPS AND/OR MYCELIA-CULTURED SOLUTION THEREOF, AND FOOD AND DRUG EACH CONTAINING THE COMPOSITION

摘要

PROBLEM TO BE SOLVED: To prevent or ameliorate cancer by compounding daily takable food with a composition with anticancer activity containing ingredients extracted from Cordyceps and/or its mycelia-cultured solution, or by compounding drugs with such a composition containing the ingredients.SOLUTION: Cordyceps and/or its mycelia-cultured solution is subjected to, according as needed, hot water extraction; subsequently, the Cordyceps and/or its mycelia-cultured solution, or a solution obtained by subjecting the Cordyceps and/or its mycelia-cultured solution to hot-water extraction, is subjected to hydrous alcohol extraction; subsequently, the resulting solution obtained by the hydrous alcohol extraction is subjected to reverse-phase column chromatography under predetermined conditions to make a crude fractionation to obtain fractions. Thereafter, a composition with anticancer activity containing ingredients contained in fractions with retention times of 4.4-5.5 min (fractions F2 to 4) among the fractions, is obtained. Using the composition, cancer can be prevented or ameliorated.