首页> 外国专利> BAFF BINDING INHIBITOR HAVING 4-(2-BENZYLIDENE HYDRAZINYL)-2-PHENYLPYRIMIDINE DERIVATIVE AS ACTIVE INGREDIENT

BAFF BINDING INHIBITOR HAVING 4-(2-BENZYLIDENE HYDRAZINYL)-2-PHENYLPYRIMIDINE DERIVATIVE AS ACTIVE INGREDIENT

机译:具有4-(2-苄叉基肼基)-2-苯并嘧啶衍生物的BAFF结合抑制剂作为活性成分

摘要

PROBLEM TO BE SOLVED: To provide a drug which inhibits the BAFF binding to a BR3 receptor and has excellent preventing and treating effects on autoimmune diseases, acquired immunodeficiency syndrome, and non-Hodgkin lymphoma.;SOLUTION: The BAFF binding inhibitor to a BR3 receptor includes a compound represented by formula (1) (wherein R1 is a 1-10C alkyl group; and R2, R3, R4, and R5 may be the same as or different from one another and are each hydrogen or a hydroxyl group), a salt thereof or a solvate thereof as an active ingredient.;COPYRIGHT: (C)2012,JPO&INPIT
机译:要解决的问题:提供一种抑制BAFF与BR3受体结合并且对自身免疫性疾病,获得性免疫缺陷综合症和非霍奇金淋巴瘤具有优异的预防和治疗作用的药物;解决方案:与BA3结合的BAFF抑制剂包括由式(1)表示的化合物(其中R 1 是1-10C烷基;并且R 2 ,R 3 ,R 4 和R 5 可以彼此相同或不同,分别为氢或羟基,其盐或它们的溶剂化物作为有效成分。;版权:(C)2012,JPO&INPIT

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