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THREE-DIMENSIONAL TISSUE-CONSTRUCTING METHOD IN PSEUDO-MICROGRAVITY ENVIRONMENT

机译:伪微重力环境中的三维组织构建方法

摘要

PROBLEM TO BE SOLVED: To provide a three-dimensional tissue-constructing method by culturing a plurality of different cell types in the pseudo-microgravity environment.;SOLUTION: The three-dimensional tissue-constructing method includes co-culturing a first cell type of at least one kind selected from the group consisting of a cell having pluripotency, a cell differentiated and derived from the cell, and a cell having deregulated proliferation potency, and a second cell type including a bone marrow cell in the pseudo-microgravity environment. Preferably, the cell having the pluripotency is selected from the group consisting of the bone marrow cell, a mesenchymal stem cell, a hematopoietic stem cell, a somatic stem cell, an iPS cell and an embryonic stem cell, and the second cell type is selected from the group consisting of a hematopoietic stem cell originated from the bone marrow cell and a floating cell component originated from the bone marrow cell.;COPYRIGHT: (C)2012,JPO&INPIT
机译:解决的问题:通过在伪微重力环境中培养多种不同的细胞类型来提供三维组织构建方法。解决方案:三维组织构建方法包括共培养第一种细胞类型。至少一种选自具有多能性的细胞,从该细胞分化和衍生的细胞,以及具有减弱的增殖能力的细胞,以及在伪微重力环境中包括骨髓细胞的第二种细胞类型。优选地,具有多能性的细胞选自骨髓细胞,间充质干细胞,造血干细胞,体细胞干细胞,iPS细胞和胚胎干细胞,并选择第二种细胞类型。来源于骨髓细胞的造血干细胞和源自骨髓细胞的浮细胞成分。;版权所有:(C)2012,JPO&INPIT

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