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Pharmaceutical composition comprising arsenous acid, its sodium salt and its derivatives intended for the treatment of urogenital cancer and its metastases
Pharmaceutical composition comprising arsenous acid, its sodium salt and its derivatives intended for the treatment of urogenital cancer and its metastases
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机译:用于治疗泌尿生殖系统癌症及其转移的包含亚砷酸,其钠盐及其衍生物的药物组合物
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摘要
The present application relates to pharmaceutical compositions and methods for treatment of urogenital diseases and bone metastasis in a human, which pharmaceutical composition contains an effective amount of arsenous acid alkaline and a pharmaceutically acceptable adjuvant. According to the present invention, the alkaline arsenous acid metal salt is sodium meta-arsenite (AsO 2 Na) or potassium meta-arsenite (AsO 2 K). The effective amount of arsenous acid alkaline is 0.0001-1500mg/kg, preferably 1-1000mg/kg, more preferably 1-150mg/kg, and most preferably 50-100mg/kg of body weight/day. The administration form of the pharmaceutical compositions of the invention is preferably oral, such as a tablet, capsule, powder and/or solution with a pharmaceutically acceptable carrier, diluent or excipient.
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