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Nectin-4 as a target gene for cancer therapy and diagnosis
Nectin-4 as a target gene for cancer therapy and diagnosis
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机译:Nectin-4作为癌症治疗和诊断的靶基因
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摘要
The present invention features methods for diagnosing cancer or assessing or determining the prognosis of a patient with lung cancer, by detecting the expression level of Nectin-4. The present invention also features double-stranded molecules against the Nectin-4 gene, vectors encoding them, compositions comprising them and methods comprising the step of administering them into a subject, which are useful for treating or preventing cancer. Also, disclosed are methods of identifying candidate compounds for treating and preventing cancer, using the Nectin-4 polypeptide or cells expressing the Nectin-4 gene.
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