Use of high molecular weight extracellular hemoglobin as a blood substitute

摘要

A blood substitute, of an extracellular haemoglobin having a molecular weight of approximately 3 to approximately 4 million daltons, comp sing chains of polymerised globins, containing free cysteines capable of binding to NO and/or SNO groups, and having a P50 of approximately 6 to approximately 7 mm Hg, and methods using the blood substitute.