PROBLEM TO BE SOLVED: To provide a metal micro-particle dispersion for immobilizing a protein immobilizing (adsorbing) the protein, etc., such as an antibody in a high ratio because a prescribed amount of a specific stabilizer is adsorbed, stably maintaining a dispersion state without aggregating even during immobilizing and/or after immobilizing of the protein and thereby suitably usable for a bio-marker or immunochromatography, etc.;SOLUTION: The metal micro-particle dispersion for immobilizing the protein comprises one or more kinds of stabilizers selected from a dibasic organic acid compound and/or a tribasic organic acid compound adsorbed on the metal micro-particle surface. The molar ratio (MMS/MM) of the number of moles (MMS) of the stabilizers to the number of moles (MM) of the metal of the metal micro-particles is within the range of 2-7. Furthermore, the dispersion contains an anionic surfactant and/or a nonionic surfactant as the stabilizers.;COPYRIGHT: (C)2007,JPO&INPIT
展开▼
机译:解决的问题:由于吸附规定量的特定稳定剂,从而稳定地维持分散液,从而以高比例提供用于固定蛋白质的金属微粒分散液,所述蛋白质固定化(吸附)蛋白质等。状态,甚至在固定化蛋白质期间和/或固定化蛋白质后也不会聚集,因此适合用于生物标记或免疫色谱法等;解决方案:用于固定蛋白质的金属微粒分散液包含一种或多种选自以下的稳定剂吸附在金属微粒表面上的二元有机酸化合物和/或三元有机酸化合物。稳定剂的摩尔数(M MS Sub>)与摩尔数(M的摩尔比(M MS Sub> / M M Sub>)金属微粒的金属的 M Sub>)在2〜7的范围内。此外,分散体还包含阴离子表面活性剂和/或非离子表面活性剂作为稳定剂。;版权所有:(C)2007,JPO&INPIT
展开▼