() The 2 (dimethyl amino) the 1 {(O (m methoxy phenethyl) the phenoxy) methyl} it designates the manufacturing method null acetonitrile of the mixed crystal of I shape crystal and II shape crystal

摘要

PROBLEM TO BE SOLVED: To provide a method for producing a mixed crystal of type I crystal and type II crystal of ()2-(dimethylamino)-1-{[O-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride useful as a pharmaceutical product.;SOLUTION: ()2-(Dimethylamino)-1-{[O-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride is recrystallized from or suspended in acetonitrile, to form a mixed crystal of type I crystal and type II crystal of ()2-(dimethylamino)-1-{[O-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride.;COPYRIGHT: (C)2009,JPO&INPIT