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Novel peptide, endotoxin-derived disease therapeutic agent using the same, and method for searching for this therapeutic agent
Novel peptide, endotoxin-derived disease therapeutic agent using the same, and method for searching for this therapeutic agent
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机译：新型肽，使用该肽的内毒素来源的疾病治疗剂以及寻找该治疗剂的方法
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摘要
Disclosed is a novel peptide showing a pharmacological effect to such a level that the peptide can be used as a prophylactic/therapeutic agent for an endotoxin-induced disease. Also disclosed is a method or means for screening of a prophylactic/therapeutic agent for an endotoxin-induced disease having a more excellent physical properties and the like by using the novel peptide. The peptide is represented by the amino acid sequence (1): XSUP0/SUPXSUP1/SUPXSUP2/SUPXSUP3/SUPXSUP4/SUPXSUP5/SUPXSUP6/SUPKVVVLLVWGSRXSUP20/SUP wherein XSUP0/SUP and XSUP20/SUP independently represent an arbitrary modification group or may be deleted; and XSUP1/SUP,SUP/XSUP2/SUP SUB, /SUB
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机译：公开了一种新颖的肽，其显示出药理学效果至可以将该肽用作内毒素诱导的疾病的预防/治疗剂的水平。还公开了通过使用新型肽来筛选具有更优异的物理性质的内毒素诱导的疾病的预防/治疗剂的方法或手段。该肽段由氨基酸序列（1）表示：X 0 X 1 X 2 X 3 X 4 X 5 X 6 KVVVLLVWGSRX 20 其中X 0 和X 20 独立代表任意修改基团，也可以删除;和X 1 ， X 2 ，
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